Dome cities are infrastructures created by the Proxies to rebuild the post-apocalyptic Earth as part of the Proxy project. They are designed to be self-sufficient and to support a small controlled population of people and their AutoReiv companions and entourages.
Each Dome was uniquely designed and sometimes merged with other domes(such as Charos and Asura). Despite this, each has a WombSys and (at least originally) was inhabited by humans and AutoReivs. It was shown that a Dome can not produce humans or function for long without a Proxy.